Immune cells divide rapidly when mounting an immune response against a pathogen, for example, or when initiating a wound-healing response. To accommodate the increased energy requirements to mount the immune response, these cells may employ metabolic pathways similar to those engaged by cancer cells—pathways such as aerobic glycolysis. This correlation presents the intriguing possibility that understanding immune cell metabolism will provide new and actionable insights into the behavior of tumor cells. In this webinar, our expert speakers will explore how this phenomenon is being studied and describe how it could enable the development of new strategies in the fight against cancer.
During the webinar, the speakers will:
• Describe how aerobic glycolysis contributes to energy production in immune cells
• Elucidate the role of lipid metabolism and mitochondrial remodeling in T-cell metabolism
• Explain how metabolic changes impact the inflammation response and innate immunity
• Answer your questions live during the broadcast!
It has recently been recognized that the role of the immune system in health and well-being is perhaps more far-reaching than previously imagined. An insufficient or overactive immune response is at the heart of countless pathologies including cancer, autoimmune diseases, and infectious diseases. Monitoring immune responses by measuring cytokine levels has become an integral part of disease-related research, providing clues to the state of the immune system and how it could be targeted therapeutically. Understanding which cytokines are best for monitoring inflammation and immunosuppression, and knowing which are secreted by different immune cell types at each stage of maturation and activation, will provide essential insights into disease treatment options. Importantly, we need to ask whether the use of common biomarkers is good enough, or if a larger number of cytokines needs to be routinely measured to better understand the complexity of immune responses.
During this webinar the speakers will address:
- The role that insufficient or overactive immune responses play in pathologies such as cancer, autoimmune diseases, and infectious diseases
- How monitoring immune responses by measuring cytokine levels has become an integral part of disease-related research
- Which cytokines are most commonly used to monitor inflammation and immunosuppression
- Which cytokines are secreted by different immune cell types following maturation and activation
- Whether the use of common biomarkers is good enough, or if a broader set of measurements is required.
The panel will answer questions live from the online audience!